1 in 4 Malaysians are affected by cancer — we aim to reduce that percentage.
Our researchers aim to:
Develop affordable and accessible methods for genetic testing for hereditary cancer, so that patients can access effective and personalised prevention.
How we’ve made a difference
Completed research showing that 1 in 9 ovarian cancers may be due to inherited alterations in the BRCA1 or BRCA2 genes. This information is now incorporated into the clinical guidelines for Malaysian doctors, and plays an important role in the development of cancer genetic services in Malaysia.
Contributed to the discovery of more than 30 genetic loci implicated in increased risk to ovarian cancer. This was made possible thanks to the many researchers from all over the world who worked collaboratively to study thousands of ovarian cancer patients and healthy women. The Malaysian ovarian cancer genetics study has made a significant contribution since it is only one of a handful of studies focused on Asians.
Worked with the International Prostate Cancer Association Consortium (PRACTICAL) and the Subang Aging Men’s Study to identify a number of genetic loci associated with increased risk to prostate cancer.
Worked with investigators at the Institute of Cancer Research to show that a blood test screening for prostate cancer is useful for its detection in people with inherited alterations in the BRCA1 and BRCA2 genes.
Completed the first mainstreaming study in Asia showing that training oncologists and surgeons to provide genetic counselling directly to patients (rather than referring them to a genetics service), increases access to genetics for patients all over the country.
What we’re doing now
Together with the Ministry of Health, we are conducting a budget impact analysis and are working towards increasing access to genetic counselling services.
More on Breast Cancer